Table 5:
Tumor to normal ratios over time for the 89Zr-scFv in two mouse backgrounds.
| Strain | nu/nu | C57Bl6/J | ||||
|---|---|---|---|---|---|---|
| Time (hr) |
0.5 | 1.5 | 2.5 | 0.5 | 1.5 | 2.5 |
| Blood | 1.59±0.1 | 3.76±0.7 | 6.16±0.2 | 0.48±0.04 | 1.79±0.2 | 1.31±0.3 |
| Liver | 1.76±0.3 | 2.03±0.2 | 2.24±0.2 | 0.66±0.06 | 1.30±0.07 | 0.45±0.07 |
| Kidneys | 7.49±6.4 | 4.61±4.37 | 1.88±0.2 | 0.66±0.43 | 4.28±3.1 | 0.39±0.3 |
| Spleen | 0.97±0.1 | 1.04±0.09 | 1.71±0.1 | 0.44±0.04 | 0.93±0.1 | 0.31±0.1 |
| Muscle | 3.24±0.6 | 5.05±0.6 | 5.22±3.2 | 1.98±0.2 | 4.21±0.7 | 3.84±0.7 |
| Bone | 1.51±0.1 | 3.44±1.65 | 1.54±1.1 | 1.99±0.1 | 2.25±0.5 | 3.57±0.3 |