Table 1.
Published equations for estimating GFR evaluated in this study
| Equation/author name | Equation for estimating GFR |
|---|---|
| Creatinine-based equation(s) | |
| Schwartzbed16 | 0.413*(Ht/Cr) |
| CysC-based equation(s) | |
| Schwartzcysc29 | 40.6 * (1.8 / CysC)0.93 |
| CKD-EPI32 | If CysC ≤ 0.8 mg/L: 133 *(CysC / 0.8)−0.499 * 0.996age [*0.932 if female] If CysC > 0.8 mg/L: 133 *(CysC / 0.8)−1.328 * 0.996age [*0.932 if female] |
| Hoek et al.28 | −4.32 + (80.35 * CysC) |
| Grubb et al.31 | 130*(CysC−1.069) * age−0.117 – 7 |
| Zappitelli et al.30 | 75.94 / (CysC1.17) |
| Combined creatinine and cystatin C-based equation(s) | |
| Full age spectrum (FAScomb)27 | 107.3 / [(Cr/QCr + CysC/QCysC) / 2]a |
a
QCr is the mean or median Cr value of the 1-year age-specific distribution of Cr in healthy children. Qcysc is 0.82 mg/L.
Cr, creatinine; CysC, cystatin C; GFR, glomerular filtration rate; Ht, height