Table 1.

The results before and 4, 8, 12 weeks after treatment with LipiFlow® in the OMGD group

Project	N	Baseline	4 weeks			8 weeks			12 weeks
		$\overline{x}\pm s$	$\overline{x}\pm s$	t	P4	$\overline{x}\pm s$	t	P8	$\overline{x}\pm s$	t	P12
SPEED	25	11.96 ± 2.46	7.72 ± 2.26	18.787	< 0.001*	4.12 ± 2.15	34.293	< 0.001*	1.52 ± 1.26	27.55	< 0.001*
OSDI	25	22.91 ± 4.42	7.61 ± 2.33	25.355	< 0.001*	3.69 ± 1.43	28.362	< 0.001*	1.74 ± 0.77	26.623	< 0.001*
SIT/mm	25	1.76 ± 1.09	6.16 ± 1.91	− 11.237	< 0.001*	4.68 ± 1.60	− 9.405	< 0.001*	3.96 ± 1.62	− 6.264	< 0.001*
NIKBUT/s	25	3.22 ± 1.47	10.97 ± 2.23	− 21.081	< 0.001*	8.13 ± 2.05	− 11.98	< 0.001*	4.37 ± 1.37	− 3.405	0.002*
TMH/mm	25	0.19 ± 0.11	0.32 ± 0.12	− 11.371	< 0.001*	0.28 ± 0.11	− 9.388	< 0.001*	0.25 ± 0.11	− 6.998	< 0.001*
LLT/nm	25	44.72 ± 10.01	75.52 ± 12.53	− 18.212	< 0.001*	68.64 ± 13.10	− 14.99	< 0.001*	61.52 ± 11.82	− 11.422	< 0.001*
PBR	25	0.58 ± 0.16	0.45 ± 0.15	14.147	< 0.001*	0.35 ± 0.12	16.545	< 0.001*	0.36 ± 0.12	13.573	< 0.001*

$\overline{x}\pm s$: mean ± standard deviation; P₄: P value at 4 weeks from baseline; P₈: P value at 8 weeks from baseline; P₁₂: P value at 12 weeks from baseline

SPEED Standard Patient Evaluation of Eye Dryness, OSDI Ocular Surface Disease Index, SIT Schirmer I test, NIKBUT noninvasive keratographic breakup time, TMH tear meniscus height, LLT lipid layer thickness, PBR partial blink rate

*Statistically significant