Table 1.
Baseline patient and tumor characteristics [n = 4038]
| RSL | WGL | p value | |
|---|---|---|---|
| [n = 1851] | [2187] | ||
| Age, years [mean (SD)] | 59.63 (9.48) | 60.35 (9.03) | 0.014 |
| DCIS size, cm [mean (SD)] | 1.84 (1.52) | 1.72 (1.38) | 0.013 |
| No. of seeds | |||
| 1 | 920 (49.7) | ||
| 2 | 101 (5.5) | ||
| 3 | 10 (0.5) | ||
| Unknowna | 820 (44.3) | 2187 (100) | |
| DCIS grade | |||
| 1 | 252 (13.6) | 295 (13.5) | < 0.001 |
| 2 | 698 (37.7) | 951 (43.5) | |
| 3 | 885 (47.8) | 919 (42.0) | |
| Unknowna | 16 (0.9) | 22 (1.0) | |
| Comedonecrosis | |||
| Absent | 68 (3.7) | 252 (11.5) | < 0.001 |
| Present | 799 (43.2) | 1002 (45.8) | |
| Unknowna | 984 (53.2) | 933 (42.7) | |
| Microcalcification | |||
| Absent | 255 (13.8) | 302 (13.8) | 0.214 |
| Present | 1012 (54.7) | 1354 (61.9) | |
| Unknowna | 584 (31.6) | 531 (24.3) | |
| Estrogen receptor | |||
| Negative | 18 (1.0) | 15 (0.7) | 0.356 |
| Positive | 37 (2.0) | 49 (2.2) | |
| Unknowna | 1796 (97.0) | 2123 (97.1) | |
| Progesteron receptor | |||
| Negative | 26 (1.4) | 23 (1.1) | 0.292 |
| Positive | 22 (1.2) | 32 (1.5) | |
| Unknowna | 1803 (97.4) | 2132 (97.5) | |
| HER2 status | |||
| Not amplified | 3 (0.2) | 1 (< 0.1) | 1 |
| Amplified | 5 (0.3) | 2 (0.1) | |
| Unknowna | 1843 (99.6) | 2184 (99.9) | |
Data are expressed as n (%) unless otherwise specified
RSL radioactive seed localization, WGL wire-guided localization, SD standard deviation, DCIS ductal carcinoma in situ, HER2 human epidermal growth factor receptor
aExcluded from the analysis
Bolded p-values indicate significance