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. 2020 Jun 23;27(13):5296–5302. doi: 10.1245/s10434-020-08744-8

Table 4.

Clinicopathological characteristics of patients with large DCIS according to the number of seeds [n = 210]a

Single seed
[n = 156 (74.3%)]
Multiple seeds (two or three)
[54 (25.7%)]
p value
Age, years [mean (SD)] 60.17 (9.60) 58.07 (10.71) 0.18
DCIS size [mean (SD)] 4.05 (1.24) 4.73 (1.62) 0.002
Resection margins [mean (SD)] 0.19 (0.20) 0.17 (0.17) 0.561
Resection margin categories
 < 2 mm 130 (83.3) 44 (81.5) 1
 ≥ 2 mm 25 (29.1) 9 (22.0)
 Unknownb 1 (0.6) 1 (1.9)
Radicality
 Free 86 (55.1) 41 (75.9) 0.025
 Focally not radical 41 (26.3) 5 (9.3)
 More than focally not radical 28 (17.9) 7 (13.0)
 Unknownb 1 (0.6) 1 (1.9)
First re-excision
 Yes 44 (28.2) 11 (20.4) 0.343
 No 112 (71.8) 43 (79.6)

Data are expressed as n (%) unless otherwise specified

DCIS ductal carcinoma in situ, SD standard deviation

aOnly patients with large DCIS (> 3 cm) with a known number of seeds were included

bExcluded from the analysis

Bolded p-values indicate significance