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Mean change in CRP and ESR levels over 48 weeks (SP2 PPS). a CRP, b ESR. Dotted lines indicate the treatment switch from ref-ADL group to SDZ-ADL group. CRP C-reactive protein, ESR erythrocyte sedimentation rate, ref-ADL reference adalimumab, SDZ-ADL Sandoz biosimilar adalimumab, SP2 PPS study period 2 per protocol set
