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. 2020 Feb 20;59(8):3581–3590. doi: 10.1007/s00394-020-02193-5

Table 1.

Baseline characteristics of the study population receiving intervention of a dietary supplementation of selenium and coenzyme Q10 combined during 4 years

Active Placebo p value
N 157 151
Age years mean (SD) 76 (3) 77 (3) 0.34
Males/females n 79/78 72/79
History
 Diabetes n (%) 32 (20.4) 29 (19.2) 0.80
 Smoking n (%) 11 (7.0) 13 (8.6) 0.60
 Hypertension n (%) 114 (72.6) 109 (72.2) 0.93
 IHD n (%) 28 (17.8) 35 (23.2) 0.25
 NYHA class I n (%) 93 (59.2) 76 (50.3) 0.12
 NYHA class II n (%) 39 (24.8) 47 (31.1) 0.22
 NYHA class III n (%) 24 (15.3) 26 (17.9) 0.65
 NYHA class IV n (%) 0 0
 BMI mean (SD) 27.4 (4.07) 27.0 (4.18) 0.44
 Hb < 120 g/L n (%) 15 (9.6) 16 (10.6) 0.76
Medications
 ACEI/ARB n (%) 30 (19.1) 40 (26.5) 0.12
 Beta blockers n (%) 56 (35.7) 53 (35.1) 0.92
 Diuretics n (%) 49 (31.2) 61 (40.4) 0.09
 Statins n (%) 35 (22.3) 32 (21.2) 0.81
Examinations
 EF < 40% n (%) 12 (7.6) 11 (7.3) 0.90
 Atrial fibrillation n (%) 9 (5.7) 12 (7.9) 0.44
 s-Selenium µg/L, mean (SD) 66.6 (15.9) 67.4 (17.2) 0.56

ACEI ACE-inhibitors, ARB angiotension receptor blockers, EF ejection fraction, IHD ischemic heart disease, NYHA New York Heart Association functional class, SD standard deviation