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. 2020 Jul 10;59(8):3369–3390. doi: 10.1007/s00394-020-02324-y

Table 1.

Microbial signatures in children with active coeliac disease relative to healthy controlsa

Study Sample source Subject details Methodology Conclusion (microbiota signatures in coeliac disease) compared to controls
[75] Stool 26 coeliac patients and 23 controls Culture

#Bacteroides

#Staphylococcus

#Clostridium
[76] Stool and duodenal biopsies 30 Coeliac patients, 30 controls PCR

Stool sample:

$Bifidobacterium count

$Bifidobacterium Longum

Duodenal biopsies:

$Bifidobacterium count

$Bifidobacterium Longum

$Bifidobacterium cantenulatum

#B. lactis
[77] Stool and duodenal biopsies 25–30 Coeliac patients, 8–30 controls PCR

Stool sample:

#E. coli prevalence and count

$Bifidobacterium count

##Clostridium leptum counts

#Staphylococcus prevalence and counts

Duodenal biopsies:

$Bifidobacterium count

#Bacteroides counts

#Clostridium leptum

#E. coli count

#Staphylococcus counts

$C. coccoides prevalence
[79] Duodenal biopsies 20 Coeliac patients, 10 controls PCR

#Bacteroides vulgatus prevalence

#E. coli prevalence
[74] Stool sample and duodenal biopsies 19 Coeliac patients, 15 controls PCR/Culture

Stool sample and duodenal Biopsies:

#Eubacteria diversity

$Lactobacillus counts

$Enterococcus counts

$Bifidobacterium counts

#Bacteroides

#Porphyromonas

#Prevotella

#Staphylococcus
[193] Stool sample 20 Coeliac patients, 20 controls PCR/Culture

#Staphylococcus epidermidis

#Staphylococcus haemolyticus

$Enterococcus faecium
[89] Duodenal biopsies 32 Coeliac patients, 8 controls Culture/ 16S rRNA sequencing

$Streptococcus mutans

$Streptococcus anginosus

$Firmicutes

#Staphylococcacea

#Staphylococcus epidermidis

#Staphylococcus pasteuri

$Streptococcaceae

#Proteobacteria

#Enterobacteriaceae

#Klebsiella oxytoca
[64] Duodenal biopsies 10 Coeliac patients, 9 controls 16S rRNA sequencing

#Prevotella melaninogenica

#Haemphilus

#Serratia

$Prevotella oralis

$Proteus

$Clostridium stercorarium

$Ruminococcus bromii

$Papllibacter cinnamivorans
[78] Duodenal biopsies 8 Coeliac Disease, 5 controls 16S rRNA gene sequencing

$Streptococcus

$Prevotella

#Neisseria

#Haemophilus

aThis table only includes the comparison of the patients with active or untreated Coeliac disease and healthy controls

#Increase in relative abundance

$Decrease in relative abundance