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. 2020 Jul 10;59(8):3369–3390. doi: 10.1007/s00394-020-02324-y

Table 2.

Microbial signatures in adults with active coeliac disease relative to healthy controlsa

Study Sample source Subject details Methodology Conclusion (microbiota signatures in coeliac disease) compared to controls
[78] Stool sample 10 Coeliac patients, 11 controls PCR

$Lactobacillus diversity

$Lactobacillus sakei

$Bifidobacterium
[84] Duodenal biopsy* 10 Treated Coeliac patients with persistent symptoms, 10 treated Coeliac patients’ symptoms free 16 S rRNA sequencing

#Proteobacteria

$Bacteroidetes

$Firmicutes
[85] Duodenal biopsy 6 Coeliac patients, 11 controls 16 S rRNA sequencing

$Bacteroidetes

$Fusobacteria
[82] Stool sample and Duodenal biopsy 23 Coeliac patients, 24 controls 16S rRNA gene sequencing

Stool sample:

$Akkermanisia

$Dorea

Duodenal biopsy:

#Helicobacter

#Megasphaera
[78] Duodenal biopsy 5 Coeliac Disease, 5 controls 16S rRNA gene sequencing

#Mycobacterium spp

#Methylobacterium spp

This table only includes the comparison of the microbial profiles in patients with active or untreated Coeliac disease and healthy controls. However, since very few studies are available in adults, we included one studya that allowed us to compare the treated coeliac patients (with persistent symptoms) with symptoms free treated Coeliac patients

#Increase in relative abundance

$Decrease in relative abundance