Table 8.
Associations between maternal blood lipids and risk of SGA across different gestational weight gain strata.
| Lipid | Unadjusted | Inadequate GWG | Appropriate GWG | Excessive GWG | |||||
|---|---|---|---|---|---|---|---|---|---|
| OR (95%CI) | P value | aOR (95%CI) d | P value | aOR (95%CI) d | P value | aOR (95%CI)a | P value | ||
| Second | |||||||||
| TC | 0.823 (0.734–0.923) | 0.001 | 0.603 (0.225–1.672) | 0.332 | 0.898 (0.629–1.582) | 0.645 | 0.753 (0.427–1.713) | 0.400 | |
| TG | 0.803 (0.684–0.935) | 0.006 | 1.014 (0.671–1.470) | 0.944 | 0.900 (0.687–1.148) | 0.421 | 0.920 (0.559–1.392) | 0.719 | |
| HDL-C | 0.771 (0.611–0.967) | 0.026 | 1.147 (0.444–2.661) | 0.770 | 0.642 (0.360–1.030) | 0.094 | 1.205 (0.527–2.314) | 0.619 | |
| LDL-C | 0.843 (0.732–0.969) | 0.017 | 1.316 (0.474–3.525) | 0.596 | 1.033 (0.586–1.427) | 0.889 | 1.108 (0.450–2.304) | 0.799 | |
| Third | |||||||||
| TC | 0.976 (0.894–1.038) | 0.557 | 0.995 (0.757–1.088) | 0.958 | 0.496 (0.333–0.741) | 0.001 | 0.545 (0.236–1.078) | 0.156 | |
| TG | 0.845 (0.767–0.926) | < 0.001 | 1.022 (0.847–1.260) | 0.816 | 1.060 (0.919–1.156) | 0.283 | 0.891 (0.619–1.243) | 0.518 | |
| HDL-C | 1.534 (1.268–1.846) | < 0.001 | 1.567 (1.022–2.607) | 0.042 | 1.900 (1.301–2.738) | 0.001 | 2.525 (1.217–5.235) | 0.013 | |
| LDL-C | 1.012 (0.904–1.132) | 0.828 | 0.824 (0.628–1.381) | 0.215 | 1.904 (1.241–2.935) | 0.003 | 1.567 (0.697–3.818) | 0.319 | |
aOR adjusted odds ratio, CI confidence interval, TC total cholesterol, TG triglycerides, LDL-C/HDL-C low-density/high-density lipoprotein cholesterol-cholesterol, GWG gestational weight gain, SGA small for gestational age.
aAdjusted for maternal age, marriage status, race, gravidity, parity, gestational age at birth, infant gender, maternal height, weight before pregnancy, anemia and FBG.