Skip to main content
. 2020 Nov 16;6:126. doi: 10.1038/s41420-020-00362-3

Table 1.

p53 CTD phosphopeptides affinity to 14-3-3 isoforms as determined by FP assay.

p53 CTD peptides Kd (μM)a
γ ε τ σ
pS366 17 ± 2 16 ± 2 28 ± 3 24 ± 4
pS378 20 ± 2 18 ± 3 27 ± 3 22 ± 3
pT387 14 ± 3 11 ± 2 24 ± 4 23 ± 3
pS366/pT387 0.14 ± 0.07 0.18 ± 0.05 6.2 ± 0.3 3.5 ± 0.4
pS366 /pS378 0.48 ± 0.05 0.51 ± 0.03 2.1 ± 0.4 2.2 ± 0.3
pS378/pT387 0.45 ± 0.03 0.80 ± 0.06 3.3 ± 0.2 7.3 ± 0.3
wt (362–393) n.q. n.q. n.q. n.q.

n.q. not quantifiable.

aValues taken from published data16