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. 2020 Nov 16;10:19901. doi: 10.1038/s41598-020-76857-x

Table 2.

Summary of clusters obtained from whole-brain regression analyses with urinary urge and void.

Cluster size (# voxels) Cluster p-value Peak Anatomical location
Z-score x (mm) y (mm) z (mm)
Void volume and slow-5 fALFF
983 4.0 × 10–10 4.31 − 2 34 − 10 Subgenual anterior cingulate (sgACC)
3.51 34 36 − 14 Lateral orbitofrontal (lOFC)
3.02 − 3 53 − 4 Medial prefrontal (mPFC)
Urinary urge and slow-5 fALFF
320 6.9 × 10–4 3.65 4 24 18 Dorsal anterior cingulate (dACC)
3.35 − 8 6 50 Supplementary motor area (SMA)
Void volume and PAG connectivity
246 2.7 × 10–3 4.03 4 − 8 36 Mid cingulate (MCC)
198 1.3 × 10–2 3.61 0 − 36 44 Posterior cingulate (PCC)
191 1.6 × 10–2 3.25 − 40 41 28 Dorsolateral prefrontal (DLPFC)
Urinary urge and PAG connectivity
283 7.8 × 10–4 3.84 − 2 2 54 Supplementary motor area (SMA)
3.68 − 2 − 4 40 Mid cingulate (MCC)
236 3.6 × 10–3 3.99 38 12 12 Anterior insula (aINS)
3.53 52 10 18 Inferior frontal gyrus (IFG)
Void volume and salience network (SLN) connectivity
275 9.7 × 10–6 4.16 − 2 − 66 − 40 Cerebellar vermis
127 1.2 × 10–2 4.04 − 54 − 18 12 Secondary somatosensory cortex (SII)
3.42 − 36 − 8 16 Posterior insula (pINS)
Void volume with default mode network (DMN) connectivity
114 2.9 × 10–2 3.80 64 − 32 42 Inferior parietal lobule (IPL)
Urinary urge with default mode network (DMN) connectivity
121 2.0 × 10–2 4.01 16 − 8 76 Primary motor (M1)
3.43 2 − 8 70 Supplementary motor area (SMA)
112 3.3 × 10–2 3.50 42 − 34 38 Inferior parietal sulcus (IPS)
Void volume with sensorimotor network (SMN) connectivity
199 4.3 × 10–4 3.48 46 − 44 40 Inferior parietal lobule (IPL)
3.40 56 − 44 22 Temporoparietal junction (TPJ)
135 1.0 × 10–2 3.55 2 44 − 8 Subgenual anterior cingulate cortex (sgACC)/ventromedial prefrontal cortex (vmPFC)
129 1.4 × 10–2 4.02 − 8 − 30 − 30 Dorsal pons