Table 2.
Aggregated findings of 16 Lymphoepithelial Carcinomas of Salivary Gland (LECSG)
| Characteristicsa | Number (n = 16) |
|---|---|
| Sex | |
| Female | 8 |
| Male | 8 |
| Age (years) | |
| Range | 18–85 |
| Mean | 55.4 |
| Median | 54.0 |
| Asian patients (mean) | 44.0 |
| White and black patients (mean) | 59.3 |
| Ethnicity | |
| White | 10 |
| Asian | 4 |
| Black | 2 |
| Symptom duration (months) | |
| Range | 3–36 |
| Mean | 11.6 |
| Clinical presentation | |
| Parotid mass | 13 (81%) |
| Submandibular mass | 3 (19%) |
| Lymph node involvement at presentation | 9 (56%) |
| Laterality | |
| Left | 10 |
| Right | 6 |
| Tumor size (cm) | |
| Range | 1.5–5.8 |
| Mean | 2.9 |
| Females (mean) | 2.3 |
| Males (mean) | 3.5 |
| Asians (mean) | 3.7 |
| Non-Asians (mean) | 2.6 |
| EBV status | |
| EBER positive (4 of 4 Asians; 4 Whites) | 8 |
| EBER negative | 8 |
| Group stage (AJCC8) | |
| I (NED, 4.5 years) | 3 |
| II (NED, 1.8 years) | 3 |
| III (NED, 7.3 years) | 4 |
| IV (2 with disease, 3.0 years; 4 NED, 3.2 years) | 6 |
| Therapy | |
| Surgery only (average follow-up: 5.9 years) | 6 |
| Surgery and radiation (average follow-up: 1.8 years) | 6 |
| Chemoradiation (average follow-up: 5.2 years) | 4 |
| Patients with follow up (n = 16) (mean years of follow-up) | |
| No evidence of disease | 14 (4.3) |
| Alive with disease | 1 (1.9) |
| Died of disease | 1 (4.2) |
| Follow up (years) | |
| Range | 0.3–10.2 |
| Mean | 4.2 |
| Follow up (years) | |
| Submandibular gland primaries (n = 3) | NED, 6.3 |
| Parotid gland primaries (n = 13) |
2 with disease, 3.0 years; 11 NED, 3.8 years |
| EBER positive (n = 8) |
2 with disease, 3.0 years; 6 NED, 5.4 years |
| EBER negative (n = 8) | NED, 3.6 |
aNot stated in all cases; AJCC8, American Joint Committee on Cancer staging manual 8th edition