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. 2020 Nov 3;8:568116. doi: 10.3389/fcell.2020.568116

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Copyright © 2020 Liu, Liu, Pan, Zhang, Qin, Chen, Li, Chen, Zheng, Liu and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Target mRNAs regulated by four candidate tsRNAs enriched in macromolecular metabolic process and their verification via qRT-PCR. (A) The general GO annotations for biological processes, cellular components, and molecular functions of the target mRNAs regulated by the four candidate tsRNAs. (B) The relative mRNA levels enriched in macromolecular metabolic process in H9c2 cells transfected with rno-tiRNA-His-004 mimics. (C) The relative mRNA levels enriched in macromolecular metabolic process in H9c2 cells transfected with rno-tRF-Cys-022 mimics. (D) The relative mRNA levels enriched in macromolecular metabolic process in H9c2 cells transfected with rno-tRF-Lys-026 mimics. (E) The relative mRNA levels enriched in macromolecular metabolic process in H9c2 cells transfected with rno-tRF-Met-008 mimics. The data are presented as the mean ± SEM (n = 3). *P < 0.05, **P < 0.01 compared with NC group.