Fig. 4.

Prior crude peanut extract (CPE) exposure promoted the development of lung inflammation and airway hyper‐reactivity (AHR). Lung slides shown at ×100 were stained with periodic acid–Schiff reagent to determine peribronchial inflammatory infiltrates and mucus production (a). Seven weeks after peripheral blood mononuclear cells (PBMC) engraftment, allergen exposure and challenge, airway resistance in response to methacholine was measured. Shown are means ± standard error of the mean (s.e.m.) of the relative change to baseline value of three independent experiments with at least three mice per group (b).