Fig. 5.

Prior crude peanut extract (CPE) exposure increased histamine release and severity of systemic anaphylactic reactions. Plasma histamine levels were measured 30 min after peanut challenge at week 7 (a). Anaphylaxis score (0–5) was determined 30 min after challenge at week 8 (b). Data from three independent experiments with five mice per group. Each point represents a mean value from three independent experiments. Scoring was performed in a blind manner by three independent investigators.