TABLE 1.
Demographic, clinical and immunological characteristics of the Kawasaki disease study population
| CD4+ T cells high: > 30%, low: < 10% | CD8+ T cells high: > 20%, low: < 6% | Illness day at diagnosis* | Sex | Age at onset (years) | Race/ethnicity | EF (%) | Z‐worst** | WBC (× 103) | Plts (× 103) | ESR (mm/h) | CRP (mg/dl) | ALT (IU/l) | GGT (IU/l) | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High mDC (> 10%) | KD 1 | Normal | Normal | 16 | M | 7·0 | Hispanic | 75·9 | 2·0 | 15·6 | 1093 | 58 | 4·4 | 93 | 656 |
| KD 2 | Normal | Normal | 4 | M | 9·1 | Hispanic | 67·0 | 0·2 | 18·0 | 299 | 66 | 6·3 | 333 | 365 | |
| High mDC Low tmDC | KD 3 | High | Low | 4 | F | 5·1 | Hispanic | 57·0 | 3·2 | 4·7 | 66 | 19 | 4·5 | 37 | 20 |
| KD 4 | Low | Low | 6 | F | 6·1 | Caucasian | 50·0 | 2·9 | 17·7 | 338 | >140 | 19·4 | 140 | 148 | |
| Low tmDC (< 6%) | KD 5 | High | High | 4 | M | 0·7 | African American | 72·3 | 4·0 | 22·8 | 394 | 62 | 21·4 | 34 | 98 |
| KD 6 | High | High | 6 | F | 0·8 | Chinese + Filipino | 65·5 | 4·6 | 16·9 | 587 | 129 | 19·6 | 44 | 51 | |
| KD 7 | High | Normal | 7 | M | 2·2 | Caucasian | 59·0 | 2·8 | 12·5 | 370 | 83 | 5·6 | 48 | 18 | |
| KD 8 | Low | Low | 11 | M | 2·3 | Caucasian | 76·0 | 3·1 | 11·0 | 362 | 76 | 7·6 | 15 | 11 | |
| KD 9 | Normal | Low | 6 | M | 3·1 | Hispanic | 69·3 | 3·9 | 21·6 | 339 | 86 | 23·4 | 78 | 62 | |
| KD 10 | Normal | High | 7 | F | 4·2 | Caucasian | 58·0 | 0·6 | 14·2 | 499 | 53 | 22 | 197 | 235 | |
| KD 11 | Normal | Normal | 4 | M | 11·8 | Filipino | 60·0 | 2·9 | 6·2 | 201 | 45 | 17·7 | 62 | 95 | |
| Others | KD 12 | High | Normal | 4 | F | 0·3 | Caucasian + Filipino | 69·4 | 2·0 | 18·5 | 401 | 66 | 7·1 | 44 | 26 |
| KD 13 | High | Normal | 5 | M | 0·4 | Caucasian + Chinese | 71·6 | 2·0 | 14·8 | 450 | 75 | 30·3 | 41 | 19 | |
| KD 14 | Normal | Normal | 6 | M | 3·5 | Filipino + Hispanic | 61·0 | 0·8 | 15·5 | 313 | 56 | 19·2 | 157 | 72 | |
| KD 15 | Normal | Normal | 7 | M | 7·8 | Hispanic | 67·0 | 2·8 | 10·7 | 279 | 102 | 13·9 | 29 | 15 | |
| KD 16 | Low | Low | 7 | M | 8·1 | Caucasian | 73·3 | 2·0 | 11·8 | 275 | 32 | 2·9 | 226 | 362 | |
| KD 17 | High | Normal | 5 | M | 9·1 | Hispanic | 63·0 | 1·3 | 7·8 | 223 | 47 | 0·6 | 80 | 145 |
a
Illness day 1 = first day of fever;
b
Z‐worst = maximum dimension during the first 6 weeks after fever onset of the right and left anterior descending coronary arteries normalized for body surface area.
EF = left ventricular ejection fraction; WBC = white blood cells; Plts = platelets; ESR = erythrocyte sedimentation rate; CRP = C‐reactive protein; ALT = alanine aminotransferase; GGT = gamma‐glutamyl transferase; mDC = myeloid dendritic cells; tmDC = tolerogenic myeloid dendritic cells.