Fig. 5.

The associations concluded for the impact of NK cell infiltration and may be influenced by IHC marker. (A) Forest plot visualizing the reported HR's of studies organized by marker used; NKp46 (orange), CD56 (dark blue), CD56 & CD57 (yellow) or CD57 (light blue). A random-effects model meta-analyses was conducted on studies using each marker. (B) This Forrest plot demonstrates the difference in the pooled risk of dying was larger in studies staining by CD56 (n = 16, HR:0.27, 0.18–0.41, p = 0.0001) and CD57 (n = 12, HR:0.38, 0.23–0.63, p = 0.0014) than NKp46 (n = 4, HR:0.58, 0.40–0.85, p = 0.020). (C) Bar graph demonstrating difference in proportion of studies finding associations between NK cell infiltration and survival when separated by marker used.