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. 2020 Aug 10;72(5):345–350. doi: 10.1016/j.ihj.2020.08.007

Table 1.

Summary of incidence of cough with perindopril in clinical studies.

Name of study/Author Type of study Perindopril Cough Incidence (%)
PIANIST23 Observational Perindopril, 10 mg 0.8
PAINT24 Observational Perindopril, 5 and 10 mg <0.1
PETRA25 Observational Perindopril, 5 mg and 10 mg 0.04
GREEK cohort60 Observational Perindopril, 5 mg and 10 mg 0.001
PROOF22 Observational Perindopril, 5 mg and 10 mg
Nedogoda SV et al.61 Randomized Perindopril 5 mg No incidence was reported (0)
Mourad JJ et al62 Randomized Perindopril, 5 mg and 10 mg 1.1
PROTECT I63 Observational Perindopril 4 mg, 8 mg 4.3
Sandeep Bansal et al.21 Perindopril, N = 1250 Monotherapy: 3.6
Combination:1.8 and 4.3
STRONG17 Perindopril, N = 427 3.2
MV Padma et al.18 Perindopril, N = 298 4

PIANIST, Perindopril-Indapamide plus AmlodipiNe in high rISk hyperTensive patients; PAINT, Perindopril-Amlodipine plus Indapamide combination for controlled hypertension Non-intervention Trial; PETRA, The Antihypertensive Efficacy of the Triple Fixed Combination of Perindopril, Indapamide, and Amlodipine; PROOF, Combined Therapy of Arterial Hypertension With a Triple Fixed-Dose Combination of Amlodipine/Indapamide/ Perindopril Arginine in Real Clinical Practice; PROTECT, Effectiveness of PeRindOpril in the management of hyperTension: idEntification of patient and physiCian determinants of response to Treatment; STRONG, SafeTy & efficacy analysis of coveRsyl amlodipine in uncOntrolled and Newly diaGnosed hypertension.