Table A5:
Aortic Valve Area and Aortic Valve Gradient
| Author, Year N (TAVI/SAVR) |
Baseline Mean (SD) |
30 Days n (%) |
1 Year n (%) |
|---|---|---|---|
| Mack et al, 201918 950 (496/454) PARTNER 3 |
Aortic valve area (cm2) TAVI: 0.8 (SE 0.16) SAVR 0.8 (SE 0.15) |
Aortic valve area (cm2) TAVI: 1.7 (SE 0.02) SAVR 1.8 (SE 0.02) Mean difference (95% CI) |
Aortic valve area (cm2) TAVI: 1.7 (SE 0.02) SAVR 1.8 (SE 0.02) Mean difference (95% CI) |
| Mean aortic valve gradient (mm Hg) TAVI: 49.4 (SE 12.79) SAVR 48.3 (11.76) |
−0.1 (−0.1 to −0.0) Mean aortic valve gradient (mm Hg) TAVI: 12.8 (SE 0.20) SAVR 11.2 (SE 0.21) Mean difference (95% CI) 1.5 (0.9 to 2.0) |
−0.1 (−0.1 to 0.0) Mean aortic valve gradient (mm Hg) TAVI: 13.7 (SE 0.26) SAVR 11.6 (SE 0.25) Mean difference (95% CI) 2.0 (1.3 to 2.7) |
|
| Popma et al, 201917 1,403 (725/678) Evolut LRT |
Not reported | N = 1,151 (610 TAVI/541 SAVR) Aortic valve area (cm2) TAVI: 2.2 (0.6) SAVR 2.0 (0.6) Mean difference (95% BCrI) 0.2 (0.1 to 0.2) N = 1,333 (699 TAVI/634 SAVR) Mean aortic valve gradient (mm Hg) TAVI: 8.4 (3.5) SAVR 10.5 (4.0) Mean difference (95% BCrI) −2.1 (−2.5 to −1.7) |
N = 634 (341 TAVI/293 SAVR) Aortic valve area (cm2) TAVI: 2.3 (0.7) SAVR 2.0 (0.6) Mean difference (95% BCrI) 0.3 (0.2 to 0.4) N = 748 (409 TAVI/339 SAVR) Mean aortic valve gradient (mm Hg) TAVI: 8.6 (3.7) SAVR 11.2 (4.9) Mean difference (95% BCrI) −2.1 (−2.5 to −1.7) |
Abbreviations: BCrI, Bayesian credible interval; SAVR, surgical aortic valve replacement; SD, standard deviation; SE, standard error; TAVI, transcatheter aortic valve implantation.