Table 1.

Number of metabolites with altered levels in response to diabetes and its treatment with insulin

	Metabolites with a changed level in 3‐month diabetic compared to non‐diabetic, age‐matched controls.	Metabolites with a normalized level in 3‐month diabetic after 1‐month insulin treatment.	Metabolites with a changed level in response to insulin treatment compared to non‐diabetic, age‐matched control.
Metabolites at increased levels (p ≤ .05)	121/607 (19.9%)	80/121 (66.1%)	19/607 (3.1%)
Metabolites at increased levels (p ≤ .1)	156/607 (25.7%)	110/156 (70.5%)	36/607 (5.9%)
Metabolites at decreased levels (p ≤ .05)	50/607 (8.2%)	32/50 (64%)	9/607 (1.5%)
Metabolites at decreased levels (p ≤ .1)	69/607 (11.4%)	45/69 (65.2%)	17/607 (2.8%)