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. 2020 Nov 16;10:19861. doi: 10.1038/s41598-020-76963-w

Table 2.

Intraclass Correlation Coefficients (ICCs).

Intraclass correlation coefficient (ICC) Significance
Single measures Average measures (p)
Variables
Angle values within the individual corneas (θ1, θ2, θ3)a 0.999 1.000 < 0.001
OCT (θA)—histology (θB) 0.858 0.924 < 0.001
Ovine animal model—human
OCT (θA) 0.792 0.862 < 0.001
Histology (θB) 0.803 0.879 < 0.001
Intra-test reliability (operator 1)
OCT (θA) 0.998 0.999 < 0.001
Histology (θB) 0.988 0.991 < 0.001
Intra-test reliability (operator 2)
OCT (θA) 0.994 0.995 < 0.001
Histology (θB) 0.983 0.987 < 0.001
Inter-test reliability (operator 1–2)
OCT (θA) 0.842 0.921 < 0.001
Histology (θB) 0.824 0.933 < 0.001

θ = Angle values within the architectural patterns. The angles (θ) have been defined as the angle formed by two linear stromal striae describing a flat figure, in the shape of the Latin letter V or X (see text). Since the two vertically opposite angles (i.e. the upper and the lower) have identical (or congruent) values according to the vertical angle theorem, only one of these was indiscriminately included in data collection.

OCT Optical coherence tomography.

aFor this analysis, three geometric structures were evaluated in each image (θ1, θ2, θ3…).