Table 3.
Correlation analysis between metric results obtained with optical coherence tomography and histology.
| Correlation coefficient | Significance | ||||||
|---|---|---|---|---|---|---|---|
| Spearman’s rho (ρ) | Kendall’s tau (τ) | (p) | |||||
| Variables | |||||||
| Ovine animal model | Angle values within the individual corneas (θ1, θ2, θ3)a | OCT | θ1, θ2 | 0.995 | 0.974 | < 0.001 | |
| θ1, θ3 | 0.994 | 0.975 | < 0.001 | ||||
| θ2, θ3 | 0.993 | 0.967 | < 0.001 | ||||
| Histology | θ1, θ2 | 0.989 | 0.971 | < 0.001 | |||
| θ1, θ3 | 0.988 | 0.969 | < 0.001 | ||||
| θ2, θ3 | 0.990 | 0.971 | < 0.001 | ||||
| OCT (θA)—histology (θB) | 0.872 | 0.775 | < 0.001 | ||||
| Human | Angle values within the individual corneas (θ1, θ2, θ3)* | OCT | θ1, θ2 | 0.993 | 0.973 | < 0.001 | |
| θ1, θ3 | 0.993 | 0.973 | < 0.001 | ||||
| θ2, θ3 | 0.992 | 0.965 | < 0.001 | ||||
| Histology | θ1, θ2 | 0.985 | 0.966 | < 0.001 | |||
| θ1, θ3 | 0.986 | 0.967 | < 0.001 | ||||
| θ2, θ3 | 0.984 | 0.965 | < 0.001 | ||||
| OCT (θA)—histology (θB) | 0.837 | 0.768 | < 0.01 | ||||
| Ovine animal model—human | OCT (θA) | 0.841 | 0.762 | < 0.01 | |||
| Histology (θB) | 0.837 | 0.765 | < 0.01 | ||||
θ = Angle values within the architectural patterns (see text).
OCT Optical coherence tomography.
aFor this analysis, three angles were evaluated for each image (θ1, θ2, θ3…).