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. 2020 Nov 16;10:19932. doi: 10.1038/s41598-020-77078-y

Table 1.

Distribution of general characteristics of included patients across all the groups.

Characteristics All eyes FCS + FCS − p value
N = 113 Vitreous adhesion group, N = 13 Vitreous detachment group, N = 6 Vitreous adhesion group, N = 48 Vitreous detachment group, N = 46
Age, year (mean ± SD) 71 ± 7 68 ± 8 71 ± 5 71 ± 6 72 ± 8 0.412
Sex (%)
Male 33 (29) 4 (31) 1 (17) 16 (33) 12 (26) 0.788
Female 80 (71) 9 (69) 5 (83) 32 (67) 34 (74)
Eye (%)
Right 48 (42) 10 (77) 3 (50) 18 (38) 17 (37) 0.364
Left 65 (58) 3 (23) 3 (50) 30 (62) 29 (63)
BCVA, logMAR (mean ± SD) 0.08 ± 0.17 0.09 ± 0.10 0.12 ± 0.12 0.09 ± 0.19 0.06 ± 0.16 0.743
FTMH size in the fellow eye, µm (mean ± SD) 461 ± 168 471 ± 229 546 ± 189 432 ± 167 476 ± 146 0.347
Refractive error, D (mean ± SD) 0.61 ± 1.62 0.09 ± 1.51 0.27 ± 2.06 1.10 ± 1.50 0.29 ± 1.64 0.451
Follow up time, months (mean ± SD) 14 ± 10 24 ± 17 15 ± 11 13 ± 10 12 ± 7 0.003*

BCVA best corrected visual acuity, logMAR logarithm of the minimal angle of resolution, FTMH full-thickness macular hole, FCS+ eyes with foveal crack sign; FCS− eyes without foveal crack sign, SD standard deviation, D diopters. Differences across the four groups were calculated using 1-way multivariate factorial ANOVA with post hoc Sidak’s test and the chi-square test according to the variables.

*Statistically significant.