Table 4.
Multivariable Regression Models of Risk Factors at Visit 4 Associated With Absolute Change in Galectin‐3 Levels From Visit 4 to Visit 5
| Variable | Coefficient (95% CI) | P Value |
|---|---|---|
| Log galectin‐3 (per log unit increase) | 0.94 (0.38–1.49) | 0.001 |
| Age, y | 0.06 (0.03–0.09) | <0.001 |
| Female | −0.55 (−0.87 to −0.22) | 0.001 |
| Black | 0.44 (0.09–0.80) | 0.01 |
| Current smoking | 0.75 (0.33–1.17) | <0.001 |
| Systolic blood pressure, mm Hg | 0.02 (0.002–0.03) | 0.03 |
| Pulse pressure, mm Hg | 0.02 (0.003–0.04) | 0.02 |
| Antihypertensive medication | 0.32 (0.03–0.61) | 0.03 |
| Body mass index, kg/m2 | 0.08 (0.05–0.11) | <0.001 |
| Diabetes mellitus | 0.81 (0.19–1.42) | 0.01 |
| Fasting glucose, mg/dL | 0.03 (0.02–0.03) | <0.001 |
| Log NT‐proBNP (per log unit increase) | 0.41 (0.27–0.55) | <0.001 |
| Log hs‐TnI (per log unit increase) | 0.23 (0.04–0.42) | 0.02 |
| Log hs‐TnT (per log unit increase) | 0.19 (−0.002 to 0.38) | 0.05 |
hs‐TNI indicates high‐sensitivity cardiac troponin I; hs‐TNT, high‐sensitivity cardiac troponin T; and NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.