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. 2020 Jun 17;9(13):e015261. doi: 10.1161/JAHA.119.015261

Table 2.

Correlation of Clinical Variables With AGEs

Variable Univariate Multivariate
r P Value Estimate SE P Value
Sexa 0.149 0.412 ··· ··· ···
Age 0.002 0.989 ··· ··· ···
Body mass index 0.344b 0.015b 0.028b 0.012b 0.034b
Heart rate 0.131 0.370 ··· ··· ···
Systolic blood pressure −0.078 0.596 ··· ··· ···
Diastolic blood pressure −0.052 0.722 ··· ··· ···
Estimate glomerular filtration rate 0.132 0.361 ··· ··· ···
C‐reactive proteinc −0.035 0.810 ··· ··· ···
Calciumc −0.039 0.787 ··· ··· ···
Phosphorusc −0.017 0.907 ··· ··· ···
Sclerostinc −0.033 0.822 ··· ··· ···
Total cholesterol 0.040 0.782 ··· ··· ···
High‐density lipoprotein cholesterol −0.164 0.260 ··· ··· ···
Triglyceridsc 0.162 0.266 ··· ··· ···
Glycated hemoglobinc 0.298b 0.038b 0.907 0.540 0.099
NT‐proBNPc −0.186 0.200 ··· ··· ···
Receptor for AGEsc −0.061 0.676 ··· ··· ···
Minimum ankle‐brachial pressure index 0.014 0.925 ··· ··· ···
Maximum IMT of carotid arteryc −0.036 0.819 ··· ··· ···
Current smokinga −0.283 0.165 ··· ··· ···
Coronary artery diseasea 0.316 0.624 ··· ··· ···
Medications ··· ··· ···
Statin usea 0.033 0.857 ··· ··· ···
Aspirin usea −0.147 0.451 ··· ··· ···
Antihypertensive agentsa −0.016 0.943 ··· ··· ···
Oral hypoglycemic agentsa 0.015 0.950 ··· ··· ···
Echocardiographic variables ··· ··· ···
Left ventricular ejection fraction 0.076 0.599 ··· ··· ···
Left ventricular diastolic diameter −0.084 0.560 ··· ··· ···
Left ventricular systolic diameter −0.105 0.469 ··· ··· ···
Interventricular septal wall thickness 0.137 0.344 ··· ··· ···
Posterior wall thickness 0.137 0.344 ··· ··· ···
Number of aortic valve 0.216 0.329 ··· ··· ···
Aortic valve peak velocity 0.091 0.528 ··· ··· ···
Aortic valve peak pressure gradientc 0.089 0.538 ··· ··· ···
Aortic valve mean pressure gradientc −0.004 0.978 ··· ··· ···
Aortic valve areac −0.048 0.742 ··· ··· ···

R 2=0.175. AGEs indicates advanced glycation end products; IMT, intima‐media thickness; and NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide.

a

Male=0, female=1 or no=0, yes=1.

b

Statistically significant values.

c

Log‐transformed value was used.