Table 3.

Correlation of Clinical Variables With sRAGE

Variable	Univariate		Multivariate
	r	P Value	Estimate	SE	P Value
Sexa	−0.071	0.691	···	···	···
Age	−0.064	0.659	···	···	···
Body mass index	−0.412b	0.003b	−0.035	0.017	0.052
Heart rate	0.131	0.370	···	···	···
Systolic blood pressure	−0.132	0.365	···	···	···
Diastolic blood pressure	−0.165	0.258	···	···	···
Estimate glomerular filtration rate	−0.699b	<0.001b	−0.008b	0.003b	0.013b
C‐reactive proteinc	0.188	0.192	···	···	···
Calciumc	0.100	0.489	···	···	···
Phosphorusc	−0.088	0.543	···	···	···
Sclerostinc	0.434b	0.002b	0.123	0.132	0.358
Total cholesterol	−0.368b	0.009b	−0.002	0.002	0.390
High‐density lipoprotein cholesterol	0.045	0.761	···	···	···
Triglyceridsc	−0.252	0.080	···	···	···
Glycated hemoglobinc	−0.386b	0.006b	−0.666	0.780	0.398
NT‐proBNPc	0.543b	<0.001b	0.047	0.037	0.211
Advanced glycation end productsc	−0.061	0.676	···	···	···
Minimum ankle‐brachial pressure index	0.039	0.793	···	···	···
Maximum IMT of carotid arteryc	−0.061	0.692	···	···	···
Current smokinga	0.040	0.836	···	···	···
Coronary artery diseasea	0.093	0.523	···	···	···
Medications			···	···	···
Statin usea	0.097	0.581	···	···	···
Aspirin usea	−0.051	0.804	···	···	···
Antihypertensive agentsa	−0.053	0.795	···	···	···
Oral hypoglycemic agentsa	−0.061	0.782	···	···	···
Echocardiographic variables			···	···	···
Left ventricular ejection fraction	0.130	0.368	···	···	···
Left ventricular diastolic diamete	0.019	0.894	···	···	···
Left ventricular systolic diameter	−0.108	0.457	···	···	···
Interventricular septal wall thickness	−0.017	0.906	···	···	···
Posterior wall thickness	0.013	0.928	···	···	···
Number of aortic valve	0.341	0.093	···	···	···
Aortic valve peak velocity	0.126	0.385	···	···	···
Aortic valve peak pressure gradientc	0.161	0.265	···	···	···
Aortic valve mean pressure gradientc	0.203	0.166	···	···	···
Aortic valve areac	0.005	0.975	···	···	···

R ²=0.586. IMT indicates intima‐media thickness; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; and sRAGE, soluble receptor for advanced glycation end products.

^aMale=0, female=1 or no=0, yes=1.

^bStatistically significant values.

^cLog‐transformed value was used.