Table 5.

Correlation of Baseline Clinical Variables With the Change in Left Ventricular Ejection Fraction

Baseline Variable	Univariate		Multivariate
	r	P Value	Estimate	SE	P Value
Sexa	−0.189	0.290	···	···	···
Age	−0.170	0.228	···	···	···
Body mass index	0.095	0.502
Heart rate	−0.028	0.846	···	···	···
Systolic blood pressure	0.012	0.936	···	···	···
Diastolic blood pressure	0.175	0.229	···	···	···
Estimate glomerular filtration rate	0.323b	0.025b	···	···	···
C‐reactive proteinc	0.054	0.715	···	···	···
Calciumc	0.033	0.823	···	···	···
Phosphorusc	0.380b	0.008b	17.717b	5.964b	0.005b
Sclerostinc	−0.168	0.253	···	···	···
Total cholesterol	0.395b	0.006b	0.057	0.040	0.156
High‐density lipoprotein cholesterol	0.093	0.535	···	···	···
Triglyceridsc	0.054	0.720	···	···	···
Glycated hemoglobinc	0.043	0.775	···	···	···
NT‐proBNPc	−0.170	0.254	···	···	···
Advanced glycation end productsc	−0.039	0.790	···	···	···
sRAGEc	−0.431b	0.002b	−5.549b	2.123b	0.012b
Minimum ankle‐brachial pressure index	0.017	0.905	···	···	···
Maximum IMT of carotid arteryc	0.231	0.132	···	···	···
Current smokinga	0.031	0.873	···	···	···
Coronary artery diseasea	0.139	0.324	···	···	···
Medication, na
Statin usea	−0.232	0.175	···	···	···
Aspirin usea	0.415b	0.025b	−4.646b	1.374b	0.002b
Antihypertensive agentsa	−0.053	0.783	···	···	···
Oral hypoglycemic agentsa	0.324	0.142	···	···	···
Echocardiographic variables
Number of aortic valve	−0.289	0.134	···	···	···
Aortic valve peak velocity	0.021	0.883	···	···	···
Aortic valve peak pressure gradientc	0.027	0.850	···	···	···
Aortic valve mean pressure gradientc	0.046	0.750	···	···	···
Aortic valve areac	−0.177	0.215	···	···	···

R ²=0.478. IMT indicates intima‐media thickness; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; and sRAGE, soluble receptor for advanced glycation end products.

^aMale=0, female=1 or no=0, yes=1.

^bStatistically significant values.

^cLog transformed value was used.