Table 2.
CMB Burdens in Each Brain Region (All Study Participants, N=49)
| Variable | Presence of CMBs, n (%) | CMB Count, Median (Range) | Brain Volume, Median (Range), cm3 | CMB Volume Ratio, Median (Range), % |
|---|---|---|---|---|
| Whole brain | 36 (73.47) | 13 (0–286) | 1526.8 (1202.8–1793.7) | 0.01 (0.00–0.20) |
| Brain regions | ||||
| Frontal | 23 (46.94) | 0 (0–64) | 484.3 (379.6–579.3) | 0.00 (0.00–0.47) |
| Parietal | 22 (44.90) | 0 (0–35) | 184.4 (150.5–224.2) | 0.00 (0.00–0.77) |
| Temporal | 29 (59.18) | 2 (0–67) | 235.4 (186.5–281.6) | 0.02 (0.00–1.03) |
| Limbic | 27 (55.10) | 1 (0–31) | 121.9 (94.8–145.4) | 0.02 (0.00–0.70) |
| Occipital | 18 (36.73) | 0 (0–31) | 149.2 (117.3–177.7) | 0.00 (0.00–0.65) |
| Caudate | 16 (32.65) | 0 (0–8) | 12.4 (7.7–16.3) | 0.00 (0.00–2.35) |
| Putamen | 21 (42.86) | 0 (0–18) | 13.2 (7.9–19.8) | 0.00 (0.00–5.30) |
| Globus pallidum | 5 (10.20) | 0 (0–8) | 6.3 (3.6–8.1) | 0.00 (0.00–4.66) |
| Thalamus | 31 (63.27) | 2 (0–56) | 17.8 (13.7–23.9) | 0.46 (0.00–12.35) |
| Corpus callosum | 2 (4.08) | 0 (0–1) | 6.4 (4.3–8.9) | 0.00 (0.00–0.11) |
| Midbrain | 9 (18.37) | 0 (0–3) | 8.0 (6.0–87.9) | 0.00 (0.00–2.99) |
| Pons | 19 (38.78) | 0 (0–16) | 14.2 (10.8–94.0) | 0.00 (0.00–7.79) |
| Medulla | 10 (20.41) | 0 (0–9) | 5.9 (4.1–85.9) | 0.00 (0.00–5.95) |
| Cerebellum | 16 (32.65) | 0 (0–23) | 150.0 (125.3–183.3) | 0.00 (0.00–1.15) |
CMB indicates cerebral microbleed.