Table 2. Baseline characteristics of the 23 studies.

Study	Study’s design	Sample sizes		Treatment		Outcomes	Course (weeks)
		Experimental	Control	Experimental	Control
Zhou 2013 [12]	RCT	15	15	TG 40 mg tid + Control group treatment	Valsartan 80–160 mg/d	24-h UTP, SCr, Alb, SGPT	8
Zhao 2011 [13]	RCT	23	23	TG 20 mg tid+Control group treatment	Valsartan160 mg qid	24-h UTP, SCr, Alb	12
Zhang 2012 [14]	RCT	50	50	1–12 weeks: TG 20 mg tid 13–24 weeks: TG 10 mg tid + Control group treatment	Irbesartan 75 mg qid–150 mg bid	24-h UTP, SCr, Alb	24
Zhang 2015 [11]	RCT	20	20	TG 1 mg/kg·d + Control group treatment	Valsartan160 mg qid	SCr, SGPT BUN, HbA1c, Alb	12
Zhang 2015 [15]	RCT	66	65	TG 30 mg bid + Control group treatment	Valsartan 80 mg qid	24-h UTP	48
Ye 2016 [16]	RCT	105	105	TG 20 mg tid + Control group treatment	Valsartan 80 mg qid	UAER, SCr	12
Yang 2016 [17]	RCT	14	16	TG 1 mg/kg·d tid + Control group treatment	Losartan 50 mg qid	24-h UTP	8
Wu 2010 [18]	RCT	32	30	TG 40 mg tid + Control group treatment	Telmisartan 80 mg bid	24-h UTP, UAER, SCr, Alb, HbA1c, SGPT	12
Wang 2013 [19]	RCT	32	30	1–8 weeks: TG 20 mg tid 9–24 weeks: TG 10 mg tid + Control group treatment	Telmisartan 40–80 mg/d	24-h UTP, SCr, BUN, HbA1c	24
Wang 2016 [20]	RCT	26	26	TG 0.3–0.5 mg/kg tid + Control group treatment	Valsartan 80 mg qid	24-h UTP	12
Wang 2012 [21]	RCT	52	30	1–8 weeks: TG 20 mg tid 9–24weeks: TG 20 mg qid + Control group treatment	Valsartan 160 mg qid	24-h UTP, UAER, SCr, Alb, HbA1c, SGPT	24
Tan 2010 [22]	RCT	25	23	1–12 weeks: TG 20 mg tid 13–24 weeks: TG 10 mg tid + Control group treatment	Irbesartan 75 mg qid–150 mg bid	24-h UTP	24
Shen 2014 [23]	RCT	90	90	TG 20 mg tid + Control group treatment	Irbesartan 150 mg bid	24-h UTP	2
Bareti 2011 [24]	RCT	43	42	1–4 weeks: TG 20 mg tid 5–12 weeks: reduce dosage by 10% per week to 10–20 mg, tid + Control group treatment	Valsartan 80–160 mg qid	24-h UTP	12
Liu 2015 [25]	RCT	30	30	TG 1 mg/kg.d + Control group treatment	Irbesartan 300 mg bid	SCr	12
Li 2013 [26]	RCT	43	43	TG 20 mg tid + Control group treatment	Valsartan 80 mg qid	UAER, SCr, Alb	36
Li 2011 [27]	RCT	20	20	TG 20 mg tid + Control group treatment	Valsartan	24-h UTP, BUN, Alb, SGPT	14
Li 2014 [28]	RCT	48	48	1–10 weeks: TG 20 mg tid 11–24 weeks: TG 10 mg tid + Control group treatment	Irbesartan 75 mg qid–150 mg bid	24-h UTP, Alb	24
Jiang 2015 [29]	RCT	62	64	TG 20 mg tid + Control group treatment	Telmisartan 80 mg qid	24-h UTP, BUN, HbA1c	12
Huang 2010 [30]	RCT	25	23	1–12 weeks: TG 20 mg tid 13–24 weeks: TG 10 mg tid + Control group treatment	Irbesartan 75 mg qid–150mg bid	24-h UTP	24
He 2010 [31]	RCT	31	29	1–8 weeks: TG 20 mg tid 9–24 weeks: TG 10 mg tid + Control group treatment	Valsartan 80–160 mg/d	24-h UTP, UAER, SCr, HbA1c, Alb	24
Tong 2012 [32]	RCT	40	35	TG 20 mg tid + Control group treatment	Losartan100 mg/d	SCr, BUN, Alb	12
Cai 2012 [33]	RCT	32	29	TG 20 mg tid + Control group treatment	Valsartan 40–80 mg qid	24-h UTP, Alb	24