Figure 2. Age-related cumulative incidence of PD, PDD, and DLB in male and female carriers of a GBA variant.

Vinicunca plot showing the cumulative incidence of the GBA-associated synucleinopathies in GBA-mutated patients (A) and according to diagnosis and sex (B). In all cases, cumulative incidence is reported as percentage (Y axis), and age reported in 20-year intervals on the X axis. (C) Pie charts report the distribution of the 4 analyzed GBA variants in patients with respect to clinical diagnosis. p Values were calculated using the χ² test. DLB = dementia with Lewy body; PD only = Parkinson disease without dementia; PDD = Parkinson with dementia.