TABLE 1.

Sample demographics

N	16,854
Age range [years]	40.2–70.3
Age (mean ± SD)	54.70 ± 7.29
Ethnic background	W 97.39 – B 0.61 – M 0.52 – A 0.67 – C 0.33 – O 0.45
Education	U 43.27 – A 13.97 – O 21.28 – C 4.14 – N 3.32 – P 5.75 – Noa 6.42
Menopausal status	Yes 50.97% – No 30.29% – Not sure 21% – Prefer not to answer 0.08%

Note: Ethnic background: W, white; B, black; M, mixed; A, Asian; C, Chinese; O, other. Educational qualification: U, university/college degree; A, A levels or equivalent; O, O levels/General Certificate of Secondary Education (GCSE) or equivalent; C, Certificate of Secondary Education (CSE) or equivalent; N, National Vocational Qualification (NVQ) or equivalent; P, professional qualification, for example, nursing/teaching; Noa, none of the above. For the categories, see http://biobank.ctsu.ox.ac.uk/crystal/coding.cgi?id=100305 and http://biobank.ctsu.ox.ac.uk/crystal/coding.cgi?id=1001. Menopausal status was based on responses to the question “Have you had your menopause?”. 10.50% answered “Not sure—had a hysterectomy,” 10.50% answered “Not sure—other reason”. N, sample size. http://biobank.ndph.ox.ac.uk/showcase/field.cgi?id=2724.