TABLE 3.
Sample demographics for apolipoprotein E type 4 (APOE e4) genotype carriers (n = 4,277) and non‐carriers (n = 11,655)
| Carriers | Non‐carriers | t | χ2 | p | N | |
|---|---|---|---|---|---|---|
| Age range (years) | 40.3–70.2 | 40.23–70.27 | 15,932 | |||
| Age (mean ± SD) | 54.4 ± 7.2 | 54.9 ± 7.3 | 942.4 | <.001 | 15,932 | |
| Number of births | 1.7 ± 1.2 | 1.7 ± 1.2 | 148.8 | <.001 | 15,924 | |
| Age at first birth (years) | 26.9 ± 5.1 | 26.9 ± 5.1 | 587.45 | <.001 | 12,583 | |
| BMI (kg/m2) | 27.5 ± 4.7 | 27.4 ± 4.8 | 712.18 | <.001 | 15,837 | |
| Age at menopause (years) | 49.7 ± 4.9 | 49.7 ± 5.0 | 937.8 | <.001 | 8,873 | |
| Estradiol (pmol/L) | 541.8 ± 439.1 | 551.5 ± 580.5 | 66.4 | <.001 | 4,346 | |
| Ever used HRT (yes) | 31.5% | 34.2% | 10.2 | <.001 | 15,904 | |
| Current HRT use (yes) | 24.7% | 21.5% | 5.5 | .02 | 4,977 | |
| Hypertension (yes) | 17.1% | 18.1% | 1.4 | .20 | 11,447 |
Note: Mean ± SD/% for each variable in each of the groups; N, sample size; BMI, body mass index; HRT, hormone replacement therapy. χ2 refers to the Pearson's chi‐square test.