Fig. 6.

Plasma concentration vs. time profiles of (a) imatinib; in the control (imatinib only) group, “imatinib+ l-GS+ l-GT” group, and “imatinib+ h-GS+ h-GT” group, in closed circles, squares, and diamonds, respectively. b N-desmethyl-imatinib; in the negative control group (imatinib only), “imatinib+ l-GS+ l-GT” group, and “imatinib+ h-GS+ h-GT” group, in open-crossed circles, squares, and diamonds, respectively. Data: mean ± SE (n = 4–6). l-GS and h-GS: low and high dose of grape seed extract, respectively. l-GT and h-GT: low and high dose of green tea extract, respectively