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. 2020 Nov 16;20:1717. doi: 10.1186/s12889-020-09813-z

Table 3.

Prevalence of comorbid disorders among problem/pathological gamblers

Disorder Number of estimates Mean comorbid prevalence (%) Community prevalence (%) RR (SE) DW
Any DSM-IV Axis 1 disorder 5a 74.8 [36.5–93.9] 20.0 [18.9–21.0] [74] 3.7 (0.74)
Any alcohol or substance use disorder 10a 22.2 [16.1–29.8] 5.1 [4.5–5.8] [74] 7.8 (0.85)
3b 57.5
Any alcohol use disorder 12a 21.2 [5.6–28.1] 8.5 (SE = 0.24) [75] 2.9 (0.68)

Very mild (0.123) [36]

Mild (0.235) [36]

Moderate (0.373) [36]

Severe (0.570) [36]

8b 28.1
 Alcohol abuse 9a 18.2 [13.4–24.2] 4.7 (SE = 0.18) [75] 3.9 (0.60)
 Alcohol dependence 7a 15.2 [10.2–22.0] 3.8 (SE = 0.14) [75] 4.0 (0.81)
Any substance (non-alcohol) use disorder 7a 7.0 [1.7–24.9] 2.0 (SE = 1.00) [75] 6.1 (4.23)
3b 17.2
 Substance (non-alcohol) abuse 8a 6.6 [3.3–12.7] 1.4 (SE = 0.08) [75] 4.7 (1.73)
 Substance (non-alcohol) dependence 6a 4.2 [1.5–11.4] 0.6 (SE = 0.05) [75] 7.0 (4.25)
 Nicotine dependence 3a 56.4 [35.7–75.2] 12.8 (SE = 0.39) [75] 4.6 (0.80)
4b 60.1
 Cannabis use disorder 3a 11.5 [4.8–25.0] 1.5 (SE = 0.08) [76] 7.7 (3.46)

Mild dependence (0.329)

Moderate to severe (0.479) [36]

Any mood disorder 10a 23.1 [14.9–34.0] 9.2 (SE = 0.22) [75] 3.3 (0.54)
3b 37.9
 Major depressive disorder 17a 29.9 [20.5–41.3] 7.1 (SE = 0.20) [75] 3.7 (0.75)

Mild (0.145) [36]

Moderate (0.396) [36]

Severe (0.658) [36]

6b 23.1
 Dysthymic disorder 3a 6.7 [4.8–9.2] 1.8 (SE = 0.09) [75] 3.7 (0.65) 0.33–0.38 [77]
 Bipolar disorder 10a 8.8 [4.4–17.1]

Mania

1.7 (SE = 0.08) [75]

5.5 (1.92)

Manic episode (0.492)

Residual state (0.032) [36]

6b 9.8
Any anxiety disorder 10a 17.6 [10.8–27.3] 11.1 (SE = 0.33) [75] 2.5 (0.39)

Mild (0.030) [36]

Moderate (0.133) [36]

Severe (0.523) [36]

3b 37.4
 Obsessive compulsive disorder (OCD) 7a 8.2 [3.4–18.6] 1.2 (SE = 0.30) [78] 6.8 (3.66) 0.12–0.60 [77]
 Panic disorder 6a 13.7 [6.7–26.0]

Without agoraphobia

1.5 (SE = 0.07) [75]

9.1 (3.31) 0.11–0.69 [77]
 Generalised anxiety disorder (GAD) 4a 14.4 [3.9–40.8] 2.1 (SE = 0.10) [75] 6.1 (4.49) 0.17–0.60 [77]
3b 11.1
 Post-traumatic stress disorder (PTSD) 4a 12.3 [3.4–35.7] 4.7 (SE = 0.17) [79] 2.6 (1.76) 0.11–0.51 [77]
 Social phobia 3a 14.9 [2.0–59.8] 2.8 (SE = 0.13) [75] 5.3 (5.27) 0.17–0.59 [77]
Other disorders
 Intermittent explosive disorder 3a 4.6 [2.5–8.4] 3.9 (SE = 0.30) [80] 1.2 (0.40)
 Kleptomania 3a 2.7 [1.2–5.9] 0.4 [0.1–1.0] [81] 6.8 (4.90)
 Psychotic disorder 5a 4.7 [3.4–6.5]

Psychosis

0.4 (SE = 0.1) [82]

11.8 (3.54)

Schizophrenia [36]

Acute state (0.778)

Residual state (0.588)

 Somatoform disorder 5a 3.6 [1.6–8.0] 0.8 [0.3–1.4] [83] 4.5 (2.58) 0.144 [84]
 Adjustment disorder 5a 9.2 [4.8–17.2] 0.3 [0.1–0.5] [85] 30.7 (14.83)
 ADHD 4a 9.3 [4.1–19.6] 4.4 (SE = 0.6) [86] 2.1 (0.94) 0.045 [36]
Any personality disorder (PD) 9c 47.9 [29.8–66.7] 7.8 [6.1–9.5] [87] 6.1 (1.39)
Any cluster A disorder 4c 6.1 [1.5–22.1] 3.8 [3.2–4.4] [87] 1.6 (1.39)
  Paranoid personality disorder 8c 10.1 [4.2–22.1] 2.3 [1.6–3.1] [87] 4.4 (2.12)
  Schizoid personality disorder 8c 6.0 [2.5–13.7] 1.1 [0.7–1.5] [87] 5.5 (2.79)
  Schizotypal personality disorder 7c 4.1 [0.8–19.4] 0.8 [0.5–1.1] [87] 5.1 (6.01)
Any cluster B disorder 4c 17.6 [6.0–41.8] 2.8 [1.8–3.7] [87] 6.3 (3.44)
  Antisocial personality disorder 14c 14.0 [10.5–18.4] 1.4 [0.8–2.3] [87] 15.3 (4.42)
2b 28.8
  Borderline personality disorder 8c 13.1 [4.3–33.5] 1.8 [1.2–2.5] [87] 7.3 (4.35) 0.193 [84]
  Histrionic personality disorder 7c 6.3 [1.0–30.4] 0.6 [0.4–0.9] [87] 10.5 (12.7)
  Narcissistic personality disorder 8c 16.6 [8.0–31.2] 1.9 [0.1–5.6] [87] 8.7 (7.16)
Any cluster C disorder 4c 12.6 [4.8–29.1] 5.0 [4.2–5.9] [87] 2.5 (1.26)
  Avoidant personality disorder 6c 13.4 [5.9–27.5] 2.7 [1.9–3.7] [87] 5.0 (2.21)
  Dependent personality disorder 8c 6.0 [1.4–22.5] 0.8 [0.5–1.3] [87] 7.5 (7.00)
  Obsessive-compulsive personality disorder 6c 13.4 [5.9–27.5] 3.2 [2.4–4.1] [87] 4.2 (1.81)

DSM-IV Diagnostic and Statistical Manual of Mental Disorders - 4th edition

a [71]; b [72]; c [73]