Figure 4.
Apoptosis inducing effect of PP-4-one in U251 and C6 cells. The incubation with PP-4-one (1.0 μM and 16 μM) or DMSO for 72 hours was followed by flow cytometry to analyze apoptosis in U251 and C6 cells. * P<0.05 and ** P<0.02 versus control cells. PP-4-one – pyrazolo[4,3-c]pyridine-4-one; DMSO – dimethyl sulfoxide.