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Effect of by PP-4-one on apoptotic proteins. The U251 and C6 cells treated with PP-4-one (1.0 μM and 16 μM) or DMSO were assessed for Bcl-2, caspase-9, caspase-3 (cleaved) and Bax levels by western blotting. PP-4-one – pyrazolo[4,3-c]pyridine-4-one; DMSO – dimethyl sulfoxide.
