Extended Data Fig. 7. Genome-wide identification of Meis1 and Hoxb13 binding sites in heart using ChIP–seq.

a, Venn diagram showing Meis1 and Hoxb13 binding-site identification. Three replicate sequencing runs were performed for each factor, and the enriched regions were selected only if they were detected in three biological replicates. b, An example of a Meis1 binding site in the cell cycle arrest gene Cdkn1b. c, Gene ontology terms enriched in Meis1-, Hoxb13- and Meis1–Hoxb13-bound peak regions identified from a.