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. 2017 Sep 2;15:186. doi: 10.1186/s12967-017-1282-9

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — a Distribution of purine motif PTS across b pyrimidine motif of RefSeq genes and genomic features associated with RefSeq genes c mixed motif. The frequency of PTS was plotted for five distinct genomic features associated with the genes including 1000 bases upstream of TSS (promoter), 5′ Untranslated region (5′UTR), Protein-coding exon (CDS), Intron, 3′ Untranslated region (3′UTR) and 1000 bases downstream of transcription end site (1000 bp down)