Table 1.
Underlying causes of hypopituitarism in the study population
| Diagnosis | Switch group (n = 105) | CA control group(n = 31) | AS control group (n = 93) |
|---|---|---|---|
| Nonfunctioning pituitary adenoma | 44 (41.9) | 5 (16.1) | 35 (37.6) |
| Craniopharyngioma | 16 (15.2) | 6 (19.4) | 5 (5.4) |
| Idiopathic | 7 (6.7) | 2 (6.5) | 9 (9.7) |
| Cushing disease | 6 (5.7) | 4 (12.9) | 4 (4.3) |
| Prolactinoma | 6 (5.7) | 5 (16.1) | 10 (10.8) |
| Empty sella syndrome | 5 (4.8) | 0 (0.0) | 3 (3.2) |
| Acromegaly | 4 (3.8) | 0 (0.0) | 7 (7.5) |
| Other diagnosis | 17 (16.2) | 9 (29.0) | 20 (21.5) |
| Other diagnosis | (n = 17) | (n = 9) | (n = 20) |
| Congenital hypopituitarism | 2 | - | 1 |
| Cystic change | 1 | - | - |
| Dysgerminoma | 1 | - | - |
| Ependymoma | - | 1 | 1 |
| Granular cell tumor | - | - | 1 |
| Histiocytosis | - | 1 | - |
| Hypophysitis | 2 | 2 | 1 |
| Isolated idiopathic GHD | - | - | 5 |
| Leukemia | - | - | 2 |
| Medulloblastoma | - | - | 1 |
| Meningioma | 2 | 1 | 3 |
| Pituitary apoplexia | 1 | 1 | 1 |
| Rhabdomyosarcoma | - | - | 1 |
| Sarcoidosis | 1 | 1 | - |
| Septo-optic dysplasia | - | 1 | - |
| Sheehan syndrome | 2 | - | - |
| Trauma | 3 | - | 1 |
| Unknown | 2 | 1 | 2 |
Data are given as No. (%).
Abbreviations: AS, adrenal sufficient; CA, cortisone acetate; GHD, growth hormone deficiency.