Table 2.
Some of the longest potential higher order quadruplex sequence (PHOQS) found in the human genome, which scores at least 50 located with method 3A (M3A)
| Entry | Chrom. | Start | Length | Runs | IL | Strand | Score | %G | %C | %A | %T | Conf.Quad.Seqs |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 11 | 400747 | 2343 | 305 | 13 | − | 58 | 66 | 17 | 7 | 10 | |
| 2 | X | 1587610 | 1666 | 293 | 37 | − | 61 | 70 | 1 | 29 | 1 | |
| 3 | 20 | 64093767 | 1646 | 151 | 13 | + | 53 | 60 | 8 | 13 | 19 | |
| 4 | 2 | 240923448 | 1351 | 156 | 0 | − | 54 | 59 | 9 | 7 | 25 | |
| 5 | X | 328170 | 1240 | 182 | 16 | − | 68 | 74 | 5 | 21 | 1 | |
| 6 | 10 | 131041965 | 1170 | 148 | 2 | + | 56 | 55 | 2 | 22 | 21 | |
| 7 | 7 | 470172 | 1125 | 136 | 0 | − | 54 | 58 | 8 | 17 | 16 | |
| 8 | 8 | 141812709 | 1102 | 142 | 8 | − | 54 | 60 | 9 | 13 | 18 | |
| 9 | 9 | 133668264 | 1089 | 189 | 11 | − | 51 | 66 | 1 | 27 | 6 | |
| 10 | X | 156029890 | 1005 | 164 | 6 | + | 52 | 56 | 0 | 13 | 31 | 26gtel4 (4), 22Ag (68), Tet22 (7), Gia18 (2), Scer21 (1) ,45Ag (51), 26gsc (1) |
| 11 | 2 | 239737366 | 990 | 163 | 4 | − | 60 | 63 | 19 | 4 | 14 | d(G4C2)4 (3) |
| 12 | 3 | 10005 | 978 | 159 | 1 | − | 52 | 55 | 2 | 15 | 29 | TSG24 (44), X3ACT (3), Tet22 (2), G4CT-pallidum (6) |
Conf.Quad.Seqs are identified G4 sequences within the found structure that are known to form in vitro, followed by the times detected in between parenthesis. Score is the mean of G4hunter and PQSfinder.
Abbreviations: Chrom.: chromosome; IL: run bulges.
%G, %C, %A and %T are percentage of that nucleotide in the sequence.