HoEBR1 analysis and dissection into its core possible PQS subunits. In black and in the first row HoEBR1, and beneath are all the possible PQS units that can potentially form the PHOQS. Sequence portions in blue are the detected G-runs, in green the run bulges and in red the loops. Score is the average between G4Hunter and PQSfinder. C. Q. S. (confirmed quadruplex sequences) are identified G4 structures within the sequence that are known to form in vitro, followed by the times detected in between parenthesis, IL is total run bulges, %G, %C, %A and %T are percentage of that nucleotide in the sequence.