Table 3.
Comparison of the top five GO terms provided by each gene set functional annotation tool
| Tool | Term | Term ID | Related genes | Cumulative related genes | Tools that also use the term |
|---|---|---|---|---|---|
| GSAn | Innate immune response-activating signal transduction | GO:0002758 | 23 | 23 | |
| T cell receptor signaling pathway | GO:0050852 | 37 | 55 | DAVID | |
| T cell costimulation | GO:0031295 | 15 | 58 | DAVID | |
| Cytokine biosynthetic process | GO:0042089 | 15 | 60 | ||
| T cell proliferation | GO:0042098 | 19 | 63 | ||
| DAVID | T cell receptor signaling pathway | GO:0050852 | 34 | 34 | GSAn |
| B cell receptor signaling pathway | GO:0050853 | 14 | 44 | ||
| T cell costimulation | GO:0031295 | 26 | 49 | GSAn | |
| Adaptive immune response | GO:0002250 | 21 | 53 | WebGestalt | |
| Immune response | GO:0006955 | 26 | 63 | ||
| g:Profiler | Immune response-activating signal transduction | GO:0002757 | 60 | 60 | |
| immune response-regulating signaling pathway | GO:0002764 | 67 | 67 | WebGestalt | |
| Positive regulation of immune system process | GO:0002684 | 68 | 70 | ||
| Regulation of immune response | GO:0050776 | 71 | 71 | ||
| Regulation of immune system process | GO:0002682 | 73 | 73 | ||
| WebGestalt | Immune response-regulating signaling pathway | GO:0002764 | 68 | 68 | g:Profiler |
| Regulation of leukocyte activation | GO:0002694 | 38 | 72 | ||
| T cell activation | GO:0042110 | 35 | 72 | ||
| Leukocyte cell-cell adhesion | GO:0007159 | 27 | 72 | ||
| Adaptive immune response | GO:0002250 | 34 | 72 | DAVID |