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CRISPR–Cas systems in L. crispatus. (A) Occurrence and diversity of CRISPR–Cas systems in 105 L. crispatus strains, color coded by CRISPR subtype. (B) CRISPR–Cas locus of subtype II-A (left) and subtype I-E (right), with signature cas gene color coded. (C) Box and whisker representation of the number of spacers detected for each CRISPR subtype and isolation source.
