Figure 3.

MiR-155 showed a better diagnostic value for active PTB from sputum

The expression levels of miR-155 in sputum specimens from 68 active Pulmonary tuberculosis (PTB) patients and 122 non-PTB patients (32 patients with pneumonia, 28 patients with lung cancer, 12 patients with unexplained pulmonary nodules and 50 healthy donors) respectively. The receiver operating characteristic curve (ROC curve) we used to evaluate the sensitivity and specificity of sputum miR-155 for active PTB diagnosis. Results showed that the sensitivity of sputum miR-155 detection was 94.1% (95% CI:86.18%-96.45%), the specificity was 87.7% (95% CI:76.13%-94.38%)