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Effect of berberine treatment on locomotion activity following METH addiction in open field test. (A) Total distance moved and distance moved in central and peripheral zone (cm), (B) Total number of crossings and number of crossings in central and peripheral zone. (Control group, n=8; METH-withdrawal group, n=7; Berberine-treated group, n=12). Data are mean±SD; (*P<0.05, **P<0.01, ***P<0.001)
METH: methamphetamine
