Table 4.
Fusion scoring from 3-dimensional reconstructed micro–computed tomography images at 6 weeks postoperative.a
|
Vitamin D Diet |
Allograft |
rhBMP-2 |
||||||
|
L3-4 |
L5-6 |
L3-4 |
L5-6 |
|||||
|
Freq. Fused (%) |
Score |
Freq. Fused (%) |
Score |
Freq. Fused (%) |
Score |
Freq. Fused (%) |
Score |
|
| Deficient | 1/8 (13) | 2.75 | 0/8 (0) | 2.67 | 7/8 (88) | 4.75 | 8/8 (100) | 4.75 |
| Rescue | 3/7 (43) | 3.50 | 0/8 (0) | 3.00 | 8/8 (100) | 4.88 | 6/7 (86) | 5.00 |
| Sufficient | 1/7 (14) | 2.86 | 0/7 (0) | 2.50 | 7/7 (100) | 4.86 | 4/7 (57) | 4.16 |
Abbreviations: rhBMP-2 indicates recombinant human bone morphogenetic protein–2; Freq., frequency.
a
Data are presented as frequency (ie, number/total), percentage, and mean fusion score. Stepwise analysis showed no effect of fusion level (L3-4 versus L5-6); thus fusion scores were compared for treatments of vitamin D diet and graft material using a χ2 test. No interactions were observed, yet there was a significant effect of graft (P < .001) where fusions with rhBMP showed improvement over those with allograft.