. 2020 Nov 13;13:837–855. doi: 10.2147/CCID.S224738

Table 1.

Lentigo Maligna (LM)/LM Melanoma (LMM) Differential Diagnosis: Clinical Presentation and Dermoscopy

	Clinical Presentation	Dermoscopy
LM/LMM⁴⁷^,¹⁵¹	Appears on chronically sun damaged skin (predominantly head and neck) Pigmented macule or patch with ill-defined borders	Polygons/rhomboids/zig-zag pattern (angulated lines) Annular-granular pattern Asymmetric pigmented follicular openings Circle within a circle
Solar lentigo¹⁵²	Multiple lesions Brown papule/plaque Darker areas can be elevated or verrucous	Moath-eaten borders Pseudonetwork Comedo-like openings Diffuse opaque-brown pigmentation Lightbrown fingerprint-like structures Milia-like cysts
Seborrheic keratosis^153–155	Appears on the torso and face Multiple lesions Sharply demarcated brown-to-black papules/plaques Can have verrucous/rough texture	Milia-like cysts Comedo-like openings Hairpin vessels Sharp demarcation and moth-eaten borders Fat fingers
LPLK¹⁵⁶^,¹⁵⁷	Solitary lesion Slightly reddish papule/plaque with smooth or verrucous surface Appears on sun-exposed trunk and upper extremities	Localized or diffuse annular granular pattern
Pigmented AK⁴⁹^,¹⁵¹	Predominantly on the face Scaly and rough surface	Annular pattern Grayish short strikes and granules Pseudoreticular structures Grayish brown dots and globules White and evident follicles Scales Brown-to-gray rhomboidal lines (without invading follicular openings) Background erythema

Abbreviations: LM/LMM, Lentigo maligna/lentigo maligna melanoma; LPLK, lichen planus like keratosis; AK, actinic keratosis.