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. 2020 Nov 13;13:897–911. doi: 10.2147/JIR.S281393

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© 2020 Yang et al.

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Extraction and identification of Syk affinitive components from PLE and their inhibited activity on Syk in vitro. (A) HPLC chromatograms: 1 – PLE, 2 – Eluent, 3 – Blank, and 4 – RosS, 5 – Vic-2, and 6 – RosA Standard reference substances. (B) Ion chromatograms (EIC) of LC-ESI-IT-TOF-MS extracted analysis of the sample peak at 18.750 min. (C) EIC of LC-ESI-IT-TOF-MS extracted analysis of the sample peak at 23.017 min. (D) EIC of LC-ESI-IT-TOF-MS extracted analysis of the sample peak at 33.300 min. (E) The relative abundance of Syk affinitive compounds as calculated by mass concentration (mg/mL) and molar concentration (mol/L). (F) In vitro Syk inhibitory activities of PLE, RosS, Vic-2, RosA, and Mix (n = 3).