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. 2020 Nov 13;15:8945–8961. doi: 10.2147/IJN.S269982

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© 2020 Cao et al.

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The three-dimensional response results of the two factors on the globule size ((A), Y₁) and drug content ((B), Y₂) after drug loading are shown. X₁: Oil phase mass percentage, X₂: Km value (Ratios of surfactant to co-surfactants).